Cell Biology. Edition: 4
Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods-from single cell RNA sequencing to second generation super resolution fluorescence microscopy-on advancing our understanding.
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- Section I Introduction to Cell Biology
- 1.Introduction to Cells
- 2.Evolution of Life on Earth
- Section II Chemical and Physical Background
- 3.Molecules: Structures and Dynamics
- 4.Biophysical Principles
- 5.Macromolecular Assembly
- 6.Research Strategies
- Section III Chromatin, Chromosomes, and the Cell Nucleus
- 7.Chromosome Organization
- 8.DNA Packaging in Chromatin and Chromosomes
- 9.Nuclear Structure and Dynamics
- Section IV Central Dogma: From Gene to Protein
- 10.Gene Expression
- 11.Eukaryotic RNA Processing
- 12.Protein Synthesis and Folding
- Section V Membrane Structure and Function
- 13.Membrane Structure and Dynamics
- 14.Membrane Pumps
- 15.Membrane Carriers
- 16.Membrane Channels
- 17.Membrane Physiology
- Section VI Cellular Organelles and Membrane Trafficking
- 18.Posttranslational Targeting of Proteins
- 19.Mitochondria, Chloroplasts, Peroxisomes
- 20.Endoplasmic Reticulum
- 21.Secretory Membrane System and Golgi Apparatus
- 22.Endocytosis and the Endosomal Membrane System
- 23.Processing and Degradation of Cellular Components
- Section VII Signaling Mechanisms
- 24.Plasma Membrane Receptors
- 25.Protein Hardware for Signaling
- 26.Second Messengers
- 27.Integration of Signals
- Section VIII Cellular Adhesion and the Extracellular Matrix
- 29.Extracellular Matrix Molecules
- 30.Cellular Adhesion
- 31.Intercellular Junctions
- 32.Connective Tissues
- Section IX Cytoskeleton and Cellular Motility
- 33.Actin and Actin-Binding Proteins
- 34.Microtubules and Centrosomes
- 35.Intermediate Filaments
- 36.Motor Proteins
- 37.Intracellular Motility
- 38.Cellular Motility
- 39.Muscles
- Section X Cell Cycle
- 40.Introduction to the Cell Cycle
- 41.G1 Phase and Regulation of Cell Proliferation
- 42.S Phase and DNA Replication
- 43.G2 Phase, Responses to DNA Damage, and Control of Entry Into Mitosis
- 44.Mitosis and Cytokinesis
- 45.Meiosis
- 46.Programmed Cell Death
- Cell SnapShots
28.Cells of the Extracellular Matrix and Immune System
Appendix
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