Medical Biochemistry. Edition: 6
Written by carefully selected global experts, practicing physicians, and educators in the various sub-disciplines of biochemistry, Medical Biochemistry, 6th Edition, offers a unique combination of research and clinical practice tailored to today's integrated courses. Covering clinically relevant topics in greater detail than other texts, this outstanding resource provides a strong overview of traditional areas in medical biochemistry along with state-of-the-art coverage of today’s latest developments. You’ll learn basic science concepts alongside clinical cases that describe patients likely to be encountered in clinical training, as well as how to use laboratory tests to diagnose and monitor the most important conditions. Thorough yet accessible, this clinically focused text is useful from medical school to clinical practice.
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SECTION 1 Introduction
1. Biochemistry and Clinical Medicine: Introduction and Overview
SECTION 2 Molecules and Cells
2. Amino Acids and Proteins
3. Carbohydrates and Lipids
4. Membranes and Transport
SECTION 3 Metabolism
5. Oxygen Transport
6. Catalytic Proteins - Enzymes
7. Vitamins and Minerals
8. Bioenergetics and Oxidative Metabolism
9. Glycolysis and the Pentose Phosphate Pathway
10. The Tricarboxylic Acid Cycle
11. Fatty Acid and Triglyceride Catabolism
12. Biosynthesis and Storage of Carbohydrate
13. Biosynthesis and Storage of Fatty Acids
14. Biosynthesis of Cholesterol and Steroids
15. Biosynthesis and Degradation of Amino Acids
16. Biosynthesis and Degradation of Nucleotides
17. Complex Carbohydrates: Glycoproteins
18. Complex Lipids
19. The Extracellular Matrix
SECTION 4 Molecular Basis of Inheritance
20. Deoxyribonucleic Acid
21. Ribonucleic Acid
22. Protein Synthesis and Turnover
23. Regulation of Gene Expression: Basic Mechanisms
24. Genomics, Proteomics and Metabolomics
SECTION 5 Signalling and Growth
25. Membrane Receptors and Signal Transduction
26. Neurotransmitters
27. Biochemical Endocrinology
28. Cellular Homeostasis: Cell Growth and Cancer
29. Aging
SECTION 6 Fuels Nutrients and Minerals
30. Digestion and Absorption of Nutrients: The Gastrointestinal Tract
31. Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus
32. Nutrients and Diets
33. Lipoprotein Metabolism and Atherogenesis
SECTION 7 Specialized Tissues and Their Function
34. Role of Liver in Metabolism
35. Water and Electrolytes Homeostasis
36. The Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)
37. Muscle: Energy Metabolism, Contraction, and Exercise
38. Bone Metabolism and Calcium Homeostasis
39. Neurochemistry
SECTION 8 Blood and Immunity. Clinical Biochemistry
40. Blood and Plasma Proteins
41. Hemostasis and Thrombosis
42. Oxidative Stress and Inflammation
43. The Immune Response: Innate and Adaptive Immunity
Appendix 1: Selected Clinical Laboratory Reference Ranges
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