Supplier to Physiotherapists, General Public, the NHS & Armed Forces

Dubois' Lupus Erythematosus and Related Syndromes. Edition: 9

Not rated yet
0

For more than 50 years, Dubois' Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It's an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.

134   – Reward points
Availability: IP - In print and in stock
    • 10% off
    £149.99, save £15.00
  • £134.99
Qty:  
In stock (116 items available)
  • Shipping info

    Our publishing partner, Elsevier, maintains a flat fee for shipping. Books are delivered in the UK via DHL and will require a signature upon delivery.

    The standard delivery time within the UK is 2 working days from the date of invoice.

    Manufactured on demand titles take an extra 3-5 working days.

    At this time we only ship Elsevier book orders to addresses within the UK.

    Brexit: We have been informed that some couriers are now charging additional fees for importing from the UK into the EU. The customer is responsible for the payment of any import duties that are in addition to the shipping costs already charged.

  • Payment methods

    logos-payments-tab_1.png

Preface, vii

List of Contributors, viii

SECTION 1 What Is Lupus?

1 History of Lupus, 1

2 Definition and Classification of Lupus and Lupus-Related

Disorders, 15

3 The Epidemiology of Lupus, 23

SECTION 2 Pathogenesis

4 Overview of Lupus Pathogenesis, 44

5 Genetics of Human SLE, 54

6 Epigenetics of Lupus, 69

7 The Environment and the Host, 86

8 The Innate Immune System in SLE, 93

9 B Cells and Generation of Antibodies, 101

10 T Cells, 116

11 Adaptive and Innate Immunoregulatory Cells, 125

12 Cytokines in Lupus, 137

13 Immunometabolism, 153

14 Animal Models in Lupus, 164

SECTION 3 Mechanisms of Tissue Injury

15 Abnormalities in Immune Complex Clearance and

Apoptotic Cell Clearance, 216

16 The Role of Complement in SLE, 224

17 Apoptosis and Inflammatory Forms of Cell Death, 237

18 Tissue Damage in Lupus: Free Radicals and Fibrosis, 248

19 Pathogenesis of Fibrosis-The Lung as a Model, 261

20 Pathogenesis of Lupus Nephritis, 269

21 Pathogenesis of Accelerated Atherosclerosis and

Vascular Injury in Systemic Lupus Erythematosus, 294

22 Pathogenesis of Cutaneous Lupus, 305

23 Pathogenesis of Neuropsychiatric Lupus, 317

24 Pathogenesis of Antiphospholipid Antibody

Syndrome, 324

25 Pathogenesis of Sjögren's, 338

SECTION 4 Autoantibodies

26 Structure and Derivation of Autoantibodies, 340

27 Antinuclear Antibodies, Antibodies to DNA, Histones, and Nucleosomes, 355

28 Antibodies Against ENA (Sm, RNP, SSA, SSB), 366

29 Antibodies Against C1q, 372

30 Antilipoprotein and Antiendothelial Cell

Antibodies, 375

31 Drug-Induced Lupus Erythematosus, 377

SECTION 5 Clinical Aspects of Lupus

Erythematosus

32 Overview and Clinical Presentation, 389

33 Skin Disease in Cutaneous Lupus Erythematosus, 395

34 The Musculoskeletal System and Bone

Metabolism, 407

35 Lupus and the Cardiopulmonary System, 418

36 Lupus and the Nervous System: Clinical Aspects, Psychopathology, and Imaging, 434

37 Gastrointestinal and Hepatic Systems, 457

38 Hematologic and Lymphoid Abnormalities in SLE, 473

39 Neonatal Lupus: Pathogenesis and Clinical

Approaches, 486

40 Pregnancy and Autoimmune Disease, Reproductive and

Hormonal Issues, 499

41 Systemic Lupus Erythematosus in Childhood and

Adolescence, 520

42 Clinical Aspects of Antiphospholipid Syndrome, 532

43 Lupus and Infections, 543

44 Ocular, Aural, and Oral Manifestations of Lupus, 556

45 Clinical Aspects of Sjögren's, 566

SECTION 6 Assessment of Lupus

46 Clinical Application of Serologic Tests, Serum Protein

Abnormalities, and Other Clinical Laboratory Tests in

Systemic Lupus Erythematosus, 579

47 Differential Diagnosis and Disease Associations, 598

48 Incomplete Lupus, Undifferentiated Connective Tissue

Disease, and Mixed Connective Tissue Disease, 606

49 Clinical Markers, Metrics, Indices, and Clinical

Trials, 614

50 Lupus Biomarkers, 631

SECTION 7 Management of Lupus

51 Principles of Therapy, Local Measures, and NSAIDs, 640

52 Antimalarial Medications, 650

53 Systemic Glucocorticoid Therapy for SLE, 661

54 Immunosuppressive Drug Therapy, 673

55 Complementary and Alternative Medications, Specialized and Niche Therapies, 689

56 Adjunctive Treatments and Preventive Measures, 702

57 Targeted Therapies in SLE, 710

58 Management of Cutaneous Lupus Erythematosus, 719

59 Epidemiology and Management of Lupus Nephritis, 727

60 Management of Sjögren's, 745

SECTION 8 Outcomes

61 Socioeconomic and Disability Aspects, 759

62 Prognosis and Mortality of SLE, 770

Index, 782

    • SKU
      9780323479271
    • UPC/ISBN
      9780323479271
    • Stock Last Checked
      Dec 5, 2021
  • Manufacturer
    Elsevier
  • Publication Date
    Oct 18, 2018
Customer reviews
There are no comments yet. Be the first to leave a comment
Please sign in to add review

Your Elsevier book orders are actioned within 48hrs during the working week. If any one item in your purchase is delayed we will send you what is in stock and will send on the remainder as soon as it arrives. This is provided at no additional shipping cost to you. Stock availability levels are updated on a daily basis.  We ship directly from a UK warehouse.

Shipping Costs

We currently maintain a flat fee structure for shipping book titles from Elsevier. Buy as many Elsevier titles as you like the we will still charge you the same single item shipping fee.

Overview Delivery Methods

Books are delivered in the UK via DHL and will require a signature upon delivery.

Deliveries within the UK

  • The standard delivery time within the UK is 2 working days from the date of invoice.
  • Print on demand titles take 3-5 working days.

Where is my order? Order Tracking

To find out more information about your order, select from the relevant options below:

Deliveries to the UK and UK shippers

Your order should be delivered to you/your shipper within 2-3 working days.

To track any deliveries using DPD, click here.

If your order is for a print on demand title, your delivery time will be longer, please allow an extra 3-5 working days.

We accept the following payment methods:

Elsevier maintains a standard returns policy